%PDF-1.4 %âăĎÓ 1 0 obj <> endobj 2 0 obj <>stream 2021-02-26T16:03:18 Adobe InDesign 15.0 (Windows) 2021-03-02T11:08:52+01:00 2021-03-02T11:08:52+01:00 Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) Prime editing;Base editing;Guide RNA design;Web application False application/pdf https://doi.org/10.1186/s12859-021-04034-6 BioMed Central BMC Bioinformatics, https://doi.org/10.1186/s12859-021-04034-6 Prime editing Base editing Guide RNA design Web application PnB Designer: a web application to design prime and base editor guide RNAs for animals and plants Sebastian M. Siegner Mehmet E. Karasu Markus S. Schröder Zacharias Kontarakis Jacob E. Corn 10.1186/s12859-021-04034-6 2010-04-23 true springer.com springerlink.com https://doi.org/10.1186/s12859-021-04034-6 10.1186/s12859-021-04034-6 1471-2105 journal BMC Bioinformatics The Author(s) 2010-04-23 true 10.1186/s12859-021-04034-6 noindex springer.com springerlink.com uuid:e44fc452-09bf-460d-b612-6d2f61b8f5a9 uuid:c0b6ac61-e847-42f0-b47f-0196d0470e83 default 1 converted uuid:e44fc452-09bf-460d-b612-6d2f61b8f5a9 converted to PDF/A-2b pdfToolbox 2021-02-27T10:07:16Z 2 B Jacob E. Corn http://orcid.org/0000-0002-7798-5309 http://ns.adobe.com/pdfx/1.3/ pdfx Adobe Document Info PDF eXtension Schema external Mirrors crossmark:MajorVersionDate CrossmarkMajorVersionDate Text external Mirrors crossmark:CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal Mirrors crossmark:DOI doi Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains seq Text internal A name object indicating whether the document has been modified to include trapping information robots Text internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://crossref.org/crossmark/1.0/ crossmark Crossmark Schema internal Usual same as prism:doi DOI Text external The date when a publication was publishe. MajorVersionDate Text internal CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal CrossMarkDomains CrossMarkDomains seq Text http://prismstandard.org/namespaces/basic/2.0/ prism Prism Schema external This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. url URI external The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). doi Text external ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. issn Text internal